Co-founded by a
Bioengineering Pioneer
Dr. Molly Shoichet is internationally renowned for her innovative biomaterials and therapeutic delivery strategies. Shoichet addresses critical questions in medicine with her multidisciplinary research approach that spans drug discovery to drug delivery.
AmacaThera is strategically positioned to develop a pipeline of products that build on cutting-edge inventions in injectable hydrogels, formulation design, drug delivery, affinity release and cell therapy.
For more information about publications related to AmacaThera’s technology, please visit the Shoichet Lab.
AmacaGel Platform
2019-03-01
A hyaluronan/methylcellulose-based hydrogel for local cell and biomolecule delivery to the central nervous system
Published in Published in Brain Research Bulletin, Mar. 2019,
2019-03-01
2010-10-02
Intrathecal delivery of a polymeric nanocomposite hydrogel after spinal cord injury
Published in Published in Biomaterials, Oct. 2010,
2010-10-02
2006-01-03
Fast-gelling injectable blend of hyaluronan and methylcellulose for intrathecal, localized delivery to the injured spinal cord.
Published in Published in Biomaterials, Jan. 2006,
2006-01-03
Biologics Cell
2020-10-14
Hydrogel-mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration
Published in Published in Biomaterials, Oct. 2020,
2020-10-14
2019-02-01
Initial cell maturity changes following transplantation in a hyaluronanbased hydrogel and impacts therapeutic success in the stroke-injured rodent brain
Published in Published in Biomaterials, Feb. 2019,
2019-02-01
2019-01-01
Controlled release strategy designed for intravitreal protein delivery to the retina.
Published in Published in Journal of Controlled Release, Jan. 2019,
2019-01-01
2016-05-13
Encapsulation-free controlled release: Electrostatic adsorption eliminates the need for protein encapsulation in PLGA nanoparticles
Published in Published in Science Advances, May 2016,
2016-05-13
2015-06-10
A Hyaluronan-Based Injectable Hydrogel Improves the Survival and Integration of Stem Cell Progeny following Transplantation
Published in Published in Stem Cell Reports, Jun. 2015,
2015-06-10
2013-11-14
Bioengineered sequential growth factor delivery stimulates brain tissue regeneration after stroke.
Published in Published in Journal of Controlled Release, Nov. 2013,
2013-11-14
2012-01-01
Tunable growth factor delivery from injectable hydrogels for tissue engineering.
Published in Published in Journal of the American Chemical Society, Jan. 2011,
2012-01-01
2011-12-16
Hydrogel delivery of erthropoietin to the brain for endogenous stem cell stimulation after stroke injury.
Published in Published in Biomaterials, Dec. 2011,
2011-12-16
Small Molecules
2015-10-14
Circumventing the blood-brain barrier: Local delivery of cyclosporin A stimulates stem cells in stroke-injured rat brain.
Published in Published in Journal of Controlled Release, Oct. 2015,
2015-10-14
2013-03-23
A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke.
Published in Published in Journal of Controlled Release, Mar. 2013,
2013-03-23
2009-12-17
Accelerated release of a sparingly soluble drug from an injectable hyaluronan-methylcellulose hydrogel.
Published in Published in Journal of Controlled Release, Dec. 2009,
2009-12-17