
AmacaThera has developed a novel hydrogel to deliver localized therapeutics. Our technology is unique. We've demonstrated GMP manufacturability and are conducting human safety testing

Injectable hydrogel transitions from liquid to gel at body temperature, ensuring drugs stay at the target site for enhanced therapeutic effect

Platform provides customizable drug release profiles burst, sustained, or combined to meet various clinical needs from post-surgical pain to oncology

AmacaThera was spun out of The Shoichet Lab as a commercial company in 2016, with support from Toronto's early-stage biotechnology sector.
developed through innovative research:

AmacaGel can deliver small molecules, growth factors, antibodies, stem cells, and enzymes

straightforward "mix and fill" process reduces production costs and supports global scalability

Targets hard-to-reach sites, including incision areas, brain, and eye tissue, for conditions ranging from post-surgical pain to oncology

Accommodates a broad range of therapeutic modalities, from small molecules and biologics to stem cells and enzymes

Shear-thinning hydrogel enables convenient dosing via pre-filled syringe, integrating smoothly into surgical workflows

Constructed from approved, well-tested materials to minimize risk and support clinical use

Clinically validated, with demonstrated safety and efficacy in both preclinical and phase 1 human trials

Flexible platform for controlled drug delivery to diverse anatomical locations, enhancing dosing and therapeutic outcomes

Strong intellectual property portfolio and readiness for GMP-scale manufacturing